Systematic review and meta-analysis methodology-Reference-Cited by-同舟云学术

Systematic review and meta-analysis methodology

Published:2010-10-28 Issue:17 Volume:116 Page:3140-3146
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Crowther Mark¹,Lim Wendy²,Crowther Mark A.²

Affiliation:

1. Department of Haematology, Worcestershire Royal Hospital, Worcester, United Kingdom; and

2. Department of Medicine, Division of Hematology-Thromboembolism, McMaster University and St. Joseph's Hospital, Hamilton, ON

Abstract

Abstract Systematic reviews and meta-analyses are being increasingly used to summarize medical literature and identify areas in which research is needed. Systematic reviews limit bias with the use of a reproducible scientific process to search the literature and evaluate the quality of the individual studies. If possible the results are statistically combined into a meta-analysis in which the data are weighted and pooled to produce an estimate of effect. This article aims to provide the reader with a practical overview of systematic review and meta-analysis methodology, with a focus on the process of performing a review and the related issues at each step.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/116/17/3140/1331008/zh804310003140.pdf

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