Human definitive hematopoietic specification from pluripotent stem cells is regulated by mesodermal expression of CDX4-Reference-Cited by-同舟云学术

Human definitive hematopoietic specification from pluripotent stem cells is regulated by mesodermal expression of CDX4

Published:2017-06-01 Issue:22 Volume:129 Page:2988-2992
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Creamer J. Philip¹,Dege Carissa¹,Ren Qihao¹,Ho Jolie T. K.¹,Valentine Mark C.²,Druley Todd E.²,Sturgeon Christopher M.¹³

Affiliation:

1. Division of Hematology, Department of Medicine,

2. Department of Pediatrics, and

3. Department of Developmental Biology, Washington University in St. Louis, St. Louis, MO

Abstract

Key Points CDX genes are differentially expressed in mesoderm harboring definitive hematopoietic potential in a WNT-dependent manner. CDX4 expression during mesoderm specification regulates human definitive hematopoietic specification.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/22/2988/1400781/blood749382.pdf

Reference22 articles.

1. Of lineage and legacy: the development of mammalian hematopoietic stem cells;Dzierzak;Nat Immunol,2008

2. Primitive erythropoiesis in the mammalian embryo;Palis;Int J Dev Biol,2010

3. T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures;Kennedy;Cell Reports,2012

4. Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells;Sturgeon;Nat Biotechnol,2014

5. Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo;de Bruijn;EMBO J,2000

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