Osteoblasts support megakaryopoiesis through production of interleukin-9-Reference-Cited by-同舟云学术

Osteoblasts support megakaryopoiesis through production of interleukin-9

Published:2017-06-15 Issue:24 Volume:129 Page:3196-3209
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Xiao Min¹²,Wang Yongkui¹²,Tao Chen¹,Wang Zhenyu²,Yang Jun¹,Chen Zhenguo¹,Zou Zhipeng¹,Li Mangmang¹,Liu Anling¹,Jia Chunhong¹,Huang Bin²,Yan Bo²,Lai Pinglin²,Ding Changhai¹,Cai Daozhang²,Xiao Guozhi³⁴,Jiang Yu⁵,Bai Xiaochun¹²

Affiliation:

1. State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences and

2. Academy of Orthopedics, Guangdong Province, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China;

3. Department of Biology and Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, China;

4. Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL; and

5. Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA

Abstract

Key Points Osteoblast-produced IL-9 supports megakaryopoiesis and platelet formation. IL-9 is a promising therapeutic agent for treatment of thrombocytopenia.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/24/3196/1401253/blood749838.pdf

Reference43 articles.

1. Platelet function and genetic testing;Angiolillo;J Am Coll Cardiol,2013

2. The incredible journey: from megakaryocyte development to platelet formation;Machlus;J Cell Biol,2013

3. Three-stage ex vivo expansion of high-ploidy megakaryocytic cells: toward large-scale platelet production;Panuganti;Tissue Eng Part A,2013

4. Osteoimmunology: interactions of the bone and immune system;Lorenzo;Endocr Rev,2008

5. Platelet transfusions for critically ill patients with thrombocytopenia;Lieberman;Blood,2014

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