Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice-Reference-Cited by-同舟云学术

Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice

Published:2017-05-04 Issue:18 Volume:129 Page:2547-2556
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Chen Zu-Lin¹,Revenko Alexey S.²,Singh Pradeep¹,MacLeod A. Robert²,Norris Erin H.¹,Strickland Sidney¹

Affiliation:

1. Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, The Rockefeller University, New York, NY; and

2. Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA

Abstract

Key PointsThe plasma contact system is activated early in AD mice and temporally correlated with the onset of brain inflammation. Depletion of contact system initiator FXII ameliorates brain pathology and cognitive impairment in AD mice.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/18/2547/1400373/blood753202.pdf

Reference63 articles.

1. Three dimensions of the amyloid hypothesis: time, space and ‘wingmen’;Musiek;Nat Neurosci,2015

2. The amyloid hypothesis of Alzheimer’s disease at 25 years;Selkoe;EMBO Mol Med,2016

3. Cerebral microinfarcts: a systematic review of neuropathological studies;Brundel;J Cereb Blood Flow Metab,2012

4. Alzheimer disease and risk of stroke: a population-based cohort study;Chi;Neurology,2013

5. Fibrinogen and altered hemostasis in Alzheimer’s disease;Cortes-Canteli;J Alzheimers Dis,2012

Cited by 71 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A multi-ethnic proteomic profiling analysis in Alzheimer’s disease identifies the disparities in dysregulation of proteins and pathogenesis;PeerJ;2024-07-18

2. Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration;APL Bioengineering;2024-05-06

3. Serum proteomic analysis in esophagectomy patients with postoperative delirium: A case-control study;Heart & Lung;2024-01

4. Sex-Specific and Traumatic Brain Injury Effects on Dopamine Receptor Expression in the Hippocampus;International Journal of Molecular Sciences;2023-11-08

5. The Venular Side of Cerebral Amyloid Angiopathy: Proof of Concept of a Neglected Issue;Biomedicines;2023-09-28