The Application of Fluorescent Antibody Methods to the Study of Platelets-Reference-Cited by-同舟云学术

The Application of Fluorescent Antibody Methods to the Study of Platelets

Published:1960-07-01 Issue:1 Volume:16 Page:958-967
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

SILBER ROBERT¹,BENITEZ ROBERTO¹,EVELAND WARREN C.¹,AKEROYD JOSEPH H.¹,DUNNE CHARLES J.¹

Affiliation:

1. Department of Immunohematology, Division of Immunology, Walter Reed Army Institute of Research, Washington, D. C., and Bacteriology Branch, Armed Forces Institute of Pathology, Washington, D. C.

Abstract

Abstract 1. Through the use of fluorescent antibody technic, it is possible to detect the antigen-antibody reaction between platelets and heterospecific antiserum, but no antigen-antibody reaction between normal human platelets and sera from patients with idiopathic thrombocytopenic purpura could be demonstrated. 2. The method permits the histologic localization of platelets in splenic tissue. 3. Whereas serum proteins can be easily removed from platelets by washing, there is an intimate association with fibrinogen so that this protein is still not removed from the platelet after 10 washings in saline.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/16/1/958/569377/958.pdf

Cited by 36 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Megakaryocyte Ultrastructure.;Annals of the New York Academy of Sciences;1987-11

2. Méthodes immunologiques d'étude des purpuras thrombopéniques idiopathiques;Revue Francaise de Transfusion et Immuno-hématologie;1981

3. Chronic idiopathic thrombocytopenic purpura;The Indian Journal of Pediatrics;1977-11

4. Experimental immunologic thrombocytopenia in dogs: a study of thrombocytopenia and megakaryocytopoiesis;Research in Veterinary Science;1977-01

5. Specific Antisera Against Human Blood Cells Applicable in the Indirect Immunofluorescence Technique;Scandinavian Journal of Immunology;1976-09