The Action of Cytostatic Agents on the Chromosomes of Human Leukocytes in Vitro (Preliminary Communication)-Reference-Cited by-同舟云学术

The Action of Cytostatic Agents on the Chromosomes of Human Leukocytes in Vitro (Preliminary Communication)

Published:1966-06-01 Issue:6 Volume:27 Page:816-823
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

HAMPEL KLAUS ERICH¹,KOBER BERNARD¹,RÖSCH DIETER¹,GERHARTZ HEINRICH¹,MEINIG KARL-HEINZ¹

Affiliation:

1. Medizinische Klinik der Freien Universitat Berlin, Division of Hematology, and Division of Nuclear Medicine, Berlin, Germany.

Abstract

Abstract Quantitative analysis of the chromosomal injuries following in vitro addition of various cytostatic agents to short-term human leukocyte cultures was carried out. The data obtained suggest that the cytogenic action of these various compounds in vitro follows a pattern similar to its action when administered therapeutically to man. The technics used may form the basis of further evaluation of the cytogenetic activity of these various compounds.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/27/6/816/572572/816.pdf

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