Prolonged Remission in Chronic Myeloid Leukemia after One Course of Busulfan-Reference-Cited by-同舟云学术

Prolonged Remission in Chronic Myeloid Leukemia after One Course of Busulfan

Published:1966-01-01 Issue:1 Volume:27 Page:103-109
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

DJALDETTI MEIR¹²,PADEH BARUCH¹³,PINKHAS JACK¹⁴,DE VRIES ANDRE¹⁵

Affiliation:

1. Department of Medicine D, Beilinson Hospital of the Labour Sickfund, Petah Tikva and the Laboratory of Cytogenetics, Tel Hashomer Government Hospital, Tel Hashomer, Israel.

2. Department of Medicine D, Beilinson Hospital of the Labour Sickfund, Petals Tiqva; Instructor in Ilematologmj, Tel-Aeiv Unieersity, Tel-Aviv, Israel.

3. Department of Medicine B, Tel-Hashomer Government Hospital; Head of Laboratory of Cytogenetics, Tel-Hashomer Government Hospital, Tel-Hashomer, Israel.

4. Department of Medicine D, Beilinson Hospital of the Labour Sickfund, Petals Tiqva, Israel.

5. Department of Medicine D., Beilinson Hospital of the Labour Sickfund, Petah Tiqva; Professor of Experimental Biology, Tel-Aciv University, Tel-Aviv, Israel.

Abstract

Abstract A patient with chronic myeloid leukemia in whom a clinical and hematologic remission of nearly 7 years duration occurred after a single short course of busulfan is described. The only abnormal finding during the remission was a negative alkaline phosphatase reaction in her leukocytes. Chromosomal studies prior to relapse revealed a normal karyotype, and no Philadelphia chromosome was found. During relapse renewed chromosomal study revealed Philadelphia chromosome in metaphases of peripheral blood leukocytes.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/27/1/103/572404/103.pdf

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