Isolated Malabsorption of Vitamin B12 Causing Megaloblastic Anemia and Hyperpigmentation in a Nigerian-Reference-Cited by-同舟云学术

Isolated Malabsorption of Vitamin B12 Causing Megaloblastic Anemia and Hyperpigmentation in a Nigerian

Published:1966-11-01 Issue:5 Volume:28 Page:770-775
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

WATSON-WILLIAMS E. J.¹²,FLEMING A. F.¹³

Affiliation:

1. Subdepartment of Hematology, University of Ibadan, Nigeria.

2. Manchester University Department of Clinical Hematology, Manchester, England.

3. Sub-Department of Hematology, University College Hospital, Ibadan, Nigeria.

Abstract

Abstract A Nigerian patient is described with megaloblastic anemia due to vitamin B12 deficiency. The deficiency resulted from malabsorption of the vitamin, but no other abnormal functioning of the gastrointestinal tract could be demonstrated. The patient did not have addisonian pernicious anemia. He had remarkable hyperpigmentation of the skin, especially of the palms of the hands. What is known of possible connections between megaloblastic anemias and melanin metabolism cannot explain this hyperpigmentation.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/28/5/770/573217/770.pdf

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