Brief Report: The Di Guglielmo Syndrome: Studies in Hemoglobin Synthesis-Reference-Cited by-同舟云学术

Brief Report: The Di Guglielmo Syndrome: Studies in Hemoglobin Synthesis

Published:1967-04-01 Issue:4 Volume:29 Page:550-553
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

NECHELES THOMAS F.¹²,DAMESHEK WILLIAM¹³

Affiliation:

1. Blood Research Laboratory, New England Medical Center Hospitals, and the Department of Medicine, Tufts University School of Medicine, Boston, Mass.

2. American Heart AssociatiOn;Assistant Hematologist, Boston Floating Hospital, New England Medical Center HospitaLs; Instructor in Medicine, Tufts University School of Medicine, Boston, Mass.

3. New England Medical Center HospitaLs, and Professor of Medicine, Tufts University School of Medicine, Boston, Mass., presently, Attending Hematologist, The Mt. Sinai Hospital, and Professor of Medicine,The Mt. Sinai School of Medicine, New York, N. Y.

Abstract

Abstract The in vitro synthesis of heme and globin has been studied in bone marrow cell suspensions obtained from five patients with Di Guglielmo syndrome. In all, a defect of heme synthesis was demonstrated, but globin synthesis was greatly reduced in only two of the five; in these two, the clinical course was a rapid one.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/29/4/550/573912/550.pdf

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