Studies on Lymphocytes. II. The Production of Lymphocytosis by Intravenous Heparin in Calves-Reference-Cited by-同舟云学术

Studies on Lymphocytes. II. The Production of Lymphocytosis by Intravenous Heparin in Calves

Published:1962-10-01 Issue:4 Volume:20 Page:443-452
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

JANSEN CORNELIUS R.¹²,CRONKITE EUGENE P.¹³,MATHER GEORGE C.¹¹,NIELSEN NIELS O.¹⁴,RAI KANTI¹¹,ADAMIK EMIL R.¹¹,SIPE CLYDE R.¹¹

Affiliation:

1. Medical Research Center, Brookhaven National Laboratory, Upton, N. Y.

2. South African Atomic Energy Board, Pretoria, South Africa Research Collaborator, Medical Research Center, Brookhaven National Laborato-ry, Upton, N. Y.

3. Division of Experimental Pathology, Medical Research Center, Brookhaven National Laboratory, Upton, N. Y.

4. Medical Research Center, Brookhaven National Laboratory, Upton, N. Y. Present address: University of Minnesota, College of Veterinary Medicine, St. Paul, Minn.

Abstract

Abstract 1. Intravenous commercial heparin produces a lymphocytosis in the calf. The effect is not due to the preservative commonly present in heparin. 2. The lymphocytosis is mediated to a great extent by an increased input of lymphocytes into the blood via the thoracic duct. 3. The necessity of considering, plus controlling the heparin effect on blood lymphocyte levels and on the output of thoracic duct lymphocytes in all studies on lymphocyte production, migration and behavior, is discussed and emphasized.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/20/4/443/570835/443.pdf

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