Crystals of Protein Nature in the Cytoplasm of Lymphatic Cells in a Case of Lymphoreticular Malignancy-Reference-Cited by-同舟云学术

Crystals of Protein Nature in the Cytoplasm of Lymphatic Cells in a Case of Lymphoreticular Malignancy

Published:1962-10-01 Issue:4 Volume:20 Page:492-500
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

DE MAN J. C. H.¹²,MEINERS W. B. H.¹³,Beens W.¹

Affiliation:

1. Pathological Laboratory, University of Leiden, and the St. Franciscus Hospital, Rotterdam, The Netherlands.

2. Pathological Laboratory, University of Leiden, Leiden, The Netherlands.

3. Department of Hematology, St. Franciscus Hospital, Rotterdam, The Netherlands.

Abstract

Abstract The occurrence of crystals in the cytoplasm of lymphatic cells in a case of lymphoreticular malignancy—probably lymphocytic leukemia—is reported. Histochemistry revealed the protein nature of these crystals. It appeared that the protein was water-soluble, with no admixture of polysaccharides. Electron microscopy of the crystals showed a fine structure of regularly arranged thin lines with a spacing of 100 Å. The crystals were surrounded by membranes of the endoplasmic reticulum.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/20/4/492/570837/492.pdf

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