The Origin of Bone Marrow Fibroblasts

Author:

de la Chapelle Albert12,Vuopio Pekka13,Borgström Georg H.12

Affiliation:

1. Folkhälsan Institute of Genetics, and the Third Department of Medicine, Institute of Genetics, Helsinki, Finland.

2. the Folkhälsan Institute of Genetics, Helsinki, Finland.

3. University of Helsinki, Helsinki, Finland.

Abstract

Abstract Bone marrow aspirates from 12 patients with malignant hematologic disorders and abnormal bone marrow karyotypes were used to establish in vitro fibroblast cultures. The karyotypes of such fibroblasts were consistently normal. This finding is at variance with results presented by others. The origin of bone marrow-derived fibroblasts remains obscure.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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