Evidence-Based Mini-Review: Is Indium-Labeled Autologous Platelet Scanning Predictive of Response to Splenectomy in Patients With Chronic Immune Thrombocytopenia?-Reference-Cited by-同舟云学术

Evidence-Based Mini-Review: Is Indium-Labeled Autologous Platelet Scanning Predictive of Response to Splenectomy in Patients With Chronic Immune Thrombocytopenia?

Published:2010-12-04 Issue:1 Volume:2010 Page:385-386
ISSN:1520-4391
Container-title:Hematology
language:en
Short-container-title:

Author:

Cuker Adam¹,Cines Douglas B.¹

Affiliation:

1. Departments of Medicine and Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA

Abstract

Abstract Clinical scenario: An otherwise healthy 25-year-old woman returns to your office for management of chronic primary immune thrombocytopenia. She was diagnosed 6 months earlier and continues to require prednisone 15 mg daily and periodic infusions of intravenous immunoglobulin to maintain a hemostatic platelet count. You discuss second-line treatment options, including splenectomy. The patient asks if there are any means by which to predict likelihood of response to splenectomy. You have heard about the use of indium-labeled autologous platelet scanning for this purpose and wonder what the evidence shows.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/hematology/article-pdf/2010/1/385/1492970/bep00110000385.pdf

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4. The interpretation of platelet kinetic studies for the identification of sites of abnormal platelet destruction;Peters;Br J Haematol,1984

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