The t(4;14)(p16.3;q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance
Author:
Affiliation:
1. Correspondence: Rafael Fonseca, Division of Hematology and Internal Medicine, Mayo Building W10B, Rochester, MN 55905;.
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/98/4/1271/1675980/h8160101271.pdf
Reference8 articles.
1. Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma.;Chesi;Blood.,2001
2. 14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma: Intergroupe Francophone du Myelome.;Avet-Loiseau;Cancer Res.,1999
3. Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell.;Gabrea;Molecular Cell.,1999
4. The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts.;Chesi;Blood.,1998
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