The t(4;14)(p16.3;q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance

Author:

Fonseca Rafael1,Oken Martin M.1,Greipp Philip R.1

Affiliation:

1. Correspondence: Rafael Fonseca, Division of Hematology and Internal Medicine, Mayo Building W10B, Rochester, MN 55905;.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference8 articles.

1. Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma.;Chesi;Blood.,2001

2. 14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma: Intergroupe Francophone du Myelome.;Avet-Loiseau;Cancer Res.,1999

3. Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell.;Gabrea;Molecular Cell.,1999

4. The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts.;Chesi;Blood.,1998

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