In vivo inhibition of low density lipoprotein receptor–related protein improves survival of factor VIII in the absence of von Willebrand factor
Author:
Affiliation:
1. Baxter Hyland ImmunoVienna, Austria
2. University of ViennaVienna, Austria
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/95/11/3637/1715854/3637.pdf
Reference7 articles.
1. Involvement of low-density lipoprotein receptor-related protein (LRP) in the clearance of factor VIII in von Willebrand factor-deficient mice.;Schwarz;Blood.,2000
2. Receptor-associated protein: a specialized chaperone and antagonist for members of the LDL receptor gene family.;Bu;Curr Opin Lipidol.,1998
3. Sequence identity between the α2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.;Strickland;J Biol Chem.,1990
4. The light chain of factor VIII comprises a binding site for low density lipoprotein receptor-related protein.;Lenting;J Biol Chem.,1999
5. A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis.;Denis;Proc Natl Acad Sci U S A.,1998
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