1. From the Department of Hematology and the Department of Internal Medicine and Medical Therapy, University of Pavia Medical School, and Instituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico S. Matteo, Pavia, Italy; the Department of Haematology, University of Wales College of Medicine, Cardiff, Wales; and the Department of Human Genetics, Mount Sinai School of Medicine, New York, NY.