The A20210 Allele of the Prothrombin Gene Is Frequently Associated With the Factor V Arg 506 to Gln Mutation But Not With Protein S Deficiency in Thrombophilic Families
Author:
Affiliation:
1. Department of Internal Medicine Lund University University Hospital Lund, Sweden
2. Department of Coagulation Disorders
3. Department of Clinical Chemistry Lund University University Hospital Malmö, Sweden
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/91/6/2210/1420938/2210.pdf
Reference9 articles.
1. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.;Poort;Blood,1996
2. Risk of venous thromboembolism associated with a G to A at position 20210 in the 3′-untranslated region of the prothrombin gene.;Brown;Br J Haematol,1997
3. The 20210 A allele of the prothrombin gene is a common risk factor among Swedish outpatients with verified deep venous thrombosis.;Hillarp;Thromb Haemost,1997
4. The venous thrombosis risk factor 20210 A allele of the prothrombin gene is not a major risk factor for arterial thrombotic disease.;Corral;Br J Haematol,1997
5. The prothrombin gene G20210A variant: Prevalence in a U.K. anticoagulant clinic population.;Cumming;Br J Haematol,1997
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