Is hydroxyurea leukemogenic in children with sickle cell disease?
Author:
Affiliation:
1. Correspondence: Mariane de Montalembert, Service de Pédiatrie Générale, Hôpital Necker-Enfants Malades, Paris, France
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/98/9/2878/1443404/h8210102875c.pdf
Reference10 articles.
1. Hydroxyurea therapy in children severely affected with sickle cell disease.;Scott;J Pediatr.,1996
2. Hydroxyurea for treatment of severe sickle cell anemia: a pediatric clinical trial.;Ferster;Blood.,1996
3. Three-year follow-up of hydroxyurea treatment in severely ill children with sickle cell disease.;De Montalembert;J Pediatr Hematol Oncol.,1997
4. Treatment of polycythemia vera: the use of hydroxyurea and pipobroman in 292 patients under the age of 65 years.;Najean;Blood.,1997
5. Acute myeloid leukemia and myelodysplastic syndrome following essential thrombocytopenia treated with hydroxyurea: high proportion of cases with 17p deletion.;Sterkers;Blood.,1998
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1. Occurrence of acute myeloid leukemia in hydroxyurea-treated sickle cell disease patient;Cancer Biology & Therapy;2019-08-18
2. POSSIBILITY OF LEUKOGENICITY EFFECT OF LONG TERM USE OF HYDROXYUREA IN SICKLE CELL ANAEMIA;Journal of Evolution of Medical and Dental Sciences;2015-06-26
3. Cytotoxicity and DNA damage in the neutrophils of patients with sickle cell anaemia treated with hydroxyurea;Brazilian Journal of Pharmaceutical Sciences;2014-04
4. DNA damage in leukocytes of sickle cell anemia patients is associated with hydroxyurea therapy and with HBB*S haplotype;Mutation Research/Genetic Toxicology and Environmental Mutagenesis;2012-12
5. Allogeneic cellular and autologous stem cell therapy for sickle cell disease: ‘whom, when and how’;Bone Marrow Transplantation;2011-12-19
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