Primary Role of the Liver in Thrombopoietin Production Shown by Tissue-Specific Knockout

Author:

Qian Shinguang1,Fu Fumin1,Li Wei1,Chen Qi2,de Sauvage Frederic J.2

Affiliation:

1. Thomas E. Starzl Transplantation Institute; Department of Surgery; University of Pittsburgh Medical Center; Pittsburgh, PA

2. Department of Molecular Oncology; Genentech Inc; South San Francisco, CA

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference11 articles.

1. Thrombopoietin: The primary regulator of megakaryocytopoiesis and thrombopoiesis.;Eaton;Exp Hematol,1997

2. Thrombopoietin: The primary regulator of platelet production.;Kaushansky;Blood,1995

3. The purification of megapoietin: A physiological regulator of megakaryocyte growth and platelet production.;Kuter;Proc Natl Acad Sci USA,1994

4. Regulation of thrombopoietin levels by c-mpl–mediated binding to platelets.;Fielder;Blood,1996

5. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-mpl ligand.;de Sauvage;Nature,1994

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