Brief Report: Philadelphia Chromosome in Acute Lymphocytic Leukemia-Reference-Cited by-同舟云学术

Brief Report: Philadelphia Chromosome in Acute Lymphocytic Leukemia

Published:1970-09-01 Issue:3 Volume:36 Page:353-360
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

PROPP SIMON¹²,LIZZI FRANK A.¹³

Affiliation:

1. Division of Hematology, Department of Medicine, Albany Medical College of Union University, Albany, N. Y.

2. Division of Hematology, Albany Medical College of Union University, Albany, N. Y.

3. Albany Medical College of Union University, Albany, N. Y. Clinical Fellow of the American Cancer Society.

Abstract

Abstract It is recognized that the Ph1 chromosome anomaly is characteristic of chronic granulocytic leukemia. It has been shown however, to occur rarely in other myeloproliferative diseases. We have reported a 53-year-old roentgenologist with acute lymphocytic leukemia who showed a high percentage of Ph1 chromosomes in his marrow cells. The possible role of radiation exposure in the production of the abnormal chromosome in this patient is discussed. The data presented is evidence against the specificity of the Ph1 chromosome for myeloproliferative disorders.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/36/3/353/754477/353.pdf

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