Functional Cytogenetic and Cytochemical Study of the Leukemic Reticulum Cells-Reference-Cited by-同舟云学术

Functional Cytogenetic and Cytochemical Study of the Leukemic Reticulum Cells

Published:1968-07-01 Issue:1 Volume:32 Page:90-101
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

YAM L. T.¹²,CASTOLDI G. L.¹²,GARVEY M. B.¹³,MITUS W. J.¹⁴

Affiliation:

1. Blood Research Laboratory, New England Medical Center Hospitals and the Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts.

2. Research Fellow in Hematology, Blood Research Laboratory, New England Medical Center Hospital and Teaching Fellow in Medicine, Tufts University School of Medicine, Boston, Mass.

3. Grant #AM 5210-06 from the National Institute of Arthritis and Metabolic Disease, Blood Research Laboratory, New England Medical Center Hospitals, Boston, Mass.

4. New England Medical Center Hospitals; Associate Professor of Medicine, Tufts University School of Medicine, Boston, Mass.

Abstract

Abstract Morphologic, cytochemical, functional, and chromosomal studies were performed on cells from blood and the spleen of a patient with leukemic reticuloendotheliosis. Characteristics of these cells were further defined by histochemical studies, by their removal by the cotton-filtration process, by their negative response to PHA stimulation, and by their poor phagocytic properties. Chromosomal studies in this case showed abnormal patterns in cells from the spleen. This abnormal pattern was characterized by the presence of an abnormal chromosome in A group, extra chromosome in C group, and monosomy in G group.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/32/1/90/575441/90.pdf

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