Brief Report: The Exacerbation of Hemolysis in Paroxysmal Nocturnal Hemoglobinuria by Strenuous Exercise-Reference-Cited by-同舟云学术

Brief Report: The Exacerbation of Hemolysis in Paroxysmal Nocturnal Hemoglobinuria by Strenuous Exercise

Published:1967-10-01 Issue:4 Volume:30 Page:513-517
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

BLUM STUART F.¹²,SULLIVAN JAY M.¹³,GARDNER FRANK H.¹²

Affiliation:

1. Richard C. Curtis Hematology Rearch Laboratory and The Cardiovascular Research Laboratory, Peter Bent Brigham Hospital, and the Department of Medicine, Harvard Medical School Boston, Mass.

2. Harvard Medical School, Boston, Mass.; present address: Presbyterian-University of Pennsylvania Medical Center, Philadelphia, Pa.

3. Harvard Medical School, Boston, Mass.

Abstract

Abstract Muscular exercise in patients with paroxysmal nocturnal hemoglobinuria has been shown to result in systemic acidosis with lacticacidemia and exacerbation of in vivo hemolysis. It is suggested on the basis of this study that patients with PNH be advised to avoid severe muscular exercise. The acid hemolysis test should be performed in all patients that are suspected of having March hemoglobinuria.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/30/4/513/573660/513.pdf

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