Relative Labeling of Leukocytes, Erythrocytes and Platelets in Human Blood by 51Chromium-Reference-Cited by-同舟云学术

Relative Labeling of Leukocytes, Erythrocytes and Platelets in Human Blood by 51Chromium

Published:1970-08-01 Issue:2 Volume:36 Page:250-253
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

EYRE HARMON J.¹²,ROSEN PETER J.¹³,PERRY SEYMOUR¹⁴

Affiliation:

1. Human Tumor Cell Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Md.

2. Human Tumor Cell Biology Branch, National Cancer Institute, NIH, Bethesda, Md.;

3. Human Tumor Cell Biology Branch, National Cancer lnstitute, NiH, Bethesda, Md.;

4. Chemotherapy, National Cancer Institute, NIH, Bethesda, Md.

Abstract

Abstract Relative labeling of peripheral blood cells by 51-chromium was determined by means of a sucrose gradient density separation technic and confirmed by radioautography. Large lymphocytes and monocytes were found to be more heavily labeled than small lymphocytes and granulocytes. Erythrocytes and platelets were relatively lightly labeled. These differences in labeling are important in evaluating data obtained when 51-chromium is utilized as a cell label for the study of leukocyte kinetics.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/36/2/250/575761/250.pdf

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