Low ectonucleotidase activity and increased neutrophil-platelet aggregates in patients with antiphospholipid syndrome-Reference-Cited by-同舟云学术

Low ectonucleotidase activity and increased neutrophil-platelet aggregates in patients with antiphospholipid syndrome

Published:2024-03-21 Issue:12 Volume:143 Page:1193-1197
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

NaveenKumar Somanathapura K.¹^ORCID,Tambralli Ajay¹²,Fonseca Bruna Mazetto¹³^ORCID,Yalavarthi Srilakshmi¹,Liang Wenying¹^ORCID,Hoy Claire K.¹,Sarosh Cyrus¹,Rysenga Christine E.¹^ORCID,Ranger Caroline H.¹,Vance Caroline E.¹,Madison Jacqueline A.¹²^ORCID,Orsi Fernanda A.³,Sood Suman L.⁴,Schaefer Jordan K.⁴^ORCID,Zuo Yu¹,Knight Jason S.¹^ORCID

Affiliation:

1. 1Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI

2. 2Division of Pediatric Rheumatology, Department of Pediatrics, University of Michigan, Ann Arbor, MI

3. 3Hematology and Hemotherapy Center, Department of Pathology, University of Campinas, Campinas, Brazil

4. 4Division of Hematology & Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI

Abstract

Abstract Many patients with antiphospholipid syndrome had decreased ectonucleotidase activity on neutrophils and platelets, which enabled extracellular nucleotides to trigger neutrophil-platelet aggregates. This phenotype was replicated by treating healthy neutrophils and platelets with patient-derived antiphospholipid antibodies or ectonucleotidase inhibitors.

Publisher

American Society of Hematology

Link

https://ashpublications.org/blood/article-pdf/143/12/1193/2218427/blood_bld-2023-022097-main.pdf

Reference16 articles.

1. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS);Miyakis;J Thromb Haemost,2006

2. NETs in APS: current knowledge and future perspectives;Tambralli;Curr Rheumatol Rep,2020

3. Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management;Knight;BMJ,2023

4. Purinergic regulation of neutrophil function;Wang;Front Immunol,2018

5. Platelet purinergic receptors in thrombosis and inflammation;Gachet;Hämostaseologie,2020

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