Anticoagulation in hospitalized patients with COVID-19

Author:

Baumann Kreuziger Lisa1ORCID,Sholzberg Michelle23ORCID,Cushman Mary45ORCID

Affiliation:

1. 1Department of Medicine Medical College of Wisconsin, Blood Research Institute, Versiti, Milwaukee, WI;

2. 2Department of Medicine and

3. 3Department of Laboratory Medicine and Pathobiology, St. Michael’s Hospital, Li Ka Shing Knowledge Institute, University of Toronto, Toronto, ON, Canada; and

4. 4Department of Medicine and

5. 5Department of Pathology & Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT

Abstract

Abstract Coronavirus disease-19 (COVID-19) includes a thromboinflammatory syndrome that may manifest with microvascular and macrovascular thrombosis. Patients with COVID-19 have a higher incidence of venous thromboembolism than other hospitalized patients. Three randomized control trials suggesting benefit of therapeutic heparin in hospitalized noncritically ill patients with COVID-19 have led to conditional guideline recommendations for this treatment. By contrast, prophylactic-dose heparin is recommended for critically ill patients. Unprecedented collaboration and rapidly funded research have improved care of hospitalized patients with COVID-19.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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