L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling-Reference-Cited by-同舟云学术

L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling

Published:2019-07-31 Issue:17 Volume:134 Page:1445-1457
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Cappenberg Anika¹,Margraf Andreas¹^ORCID,Thomas Katharina¹,Bardel Bernadette¹,McCreedy Dylan A.²³,Van Marck Veerle⁴,Mellmann Alexander⁵^ORCID,Lowell Clifford A.³,Zarbock Alexander¹

Affiliation:

1. Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Muenster, Germany;

2. Department of Biology, Texas A&M University, College Station, TX;

3. Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA;

4. Gerhard-Domagk-Institute of Pathology University of Muenster, Albert-Schweitzer-Campus 1, Muenster, Germany; and

5. Institute of Hygiene, University Hospital Muenster, Muenster, Germany

Abstract

This study unveils an unanticipated role of L-selectin downstream of integrin outside-in signaling in important neutrophil effector functions, including the clearance of bacteria in infected tissues.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/134/17/1445/1502461/bloodbld2019000685.pdf

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