BCL2 inhibition: back to the future!
Author:
Affiliation:
1. University of Leicester
Publisher
American Society of Hematology
Link
https://ashpublications.org/blood/article-pdf/143/18/1787/2223709/blood_bld-2023-023796-c-main.pdf
Reference10 articles.
1. Sonrotoclax overcomes BCL2 G101V mutation–induced venetoclax resistance in preclinical models of hematologic malignancy;Liu;Blood,2024
2. Targeting anti-apoptotic BCL2 family proteins in haematological malignancies—from pathogenesis to treatment;Vogler;Br J Haematol,2017
3. An inhibitor of Bcl-2 family proteins induces regression of solid tumours;Oltersdorf;Nature,2005
4. Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors;Gandhi;J Clin Oncol,2011
5. ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets;Souers;Nat Med,2013
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