Connecting the dots from let-7 to HIC2 to HBG
Author:
Affiliation:
1. National Institute of Diabetes and Digestive and Kidney Diseases
Publisher
American Society of Hematology
Link
https://ashpublications.org/blood/article-pdf/143/19/1886/2224728/blood_bld-2024-024191-c-main.pdf
Reference7 articles.
1. let-7 miRNAs repress HIC2 to regulate BCL11A transcription and hemoglobin switching;Huang;Blood,2024
2. Direct promoter repression by BCL11A controls the fetal to adult hemoglobin switch;Liu;Cell,2018
3. Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding;Martyn;Nat Genet,2018
4. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level;Bauer;Science,2013
5. HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription;Huang;Nat Genet,2023
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