Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know-Reference-Cited by-同舟云学术

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know

Published:2021-06-01 Issue:4 Volume:138 Page:293-298
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Arepally Gowthami M.¹^ORCID,Ortel Thomas L.¹^ORCID

Affiliation:

1. Division of Hematology, Duke University Medical Center, Durham, NC

Abstract

Abstract The development of vaccines to fight COVID-19 has been a remarkable medical achievement. However, this global immunization effort has been complicated by a rare vaccine-related outcome characterized by thrombocytopenia and thrombosis in association with platelet-activating anti–platelet factor 4 antibodies. In this Spotlight, we will discuss the recently described complication of vaccine-induced immune thrombotic thrombocytopenia (VITT) occurring in response to certain COVID-19 vaccines. Although information about this clinical condition is rapidly evolving, we will summarize our current understanding of VITT.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/138/4/293/1815524/bloodbld2021012152c.pdf

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