Lenalidomide in follicular lymphoma

Author:

Flowers Christopher R.1,Leonard John P.23,Fowler Nathan H.1

Affiliation:

1. Department of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX;

2. Department of Medicine, Weill Medical College of Cornell University, New York, NY; and

3. New York Presbyterian Hospital, New York, NY

Abstract

Abstract Lenalidomide is an immunomodulatory drug approved in the United States for use with rituximab in patients with relapsed/refractory follicular lymphoma. We reviewed data from trials addressing the safety and efficacy of lenalidomide alone and in combination with rituximab as a first-line therapy and as a treatment of patients with relapsed/refractory follicular lymphoma. Lenalidomide-rituximab has been demonstrated to be an effective chemotherapy-free therapy that improves upon single-agent rituximab and may become an alternative to chemoimmunotherapy.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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