Sepsis alters the transcriptional and translational landscape of human and murine platelets-Reference-Cited by-同舟云学术

Sepsis alters the transcriptional and translational landscape of human and murine platelets

Published:2019-07-31 Issue:12 Volume:134 Page:911-923
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Middleton Elizabeth A.¹²,Rowley Jesse W.¹²,Campbell Robert A.¹³,Grissom Colin K.²⁴,Brown Samuel M.²⁴,Beesley Sarah J.²⁴^ORCID,Schwertz Hansjörg¹⁵,Kosaka Yasuhiro¹,Manne Bhanu K.¹^ORCID,Krauel Krystin¹,Tolley Neal D.¹,Eustes Alicia S.¹⁶,Guo Li¹,Paine Robert²⁷,Harris Estelle S.²,Zimmerman Guy A.¹²,Weyrich Andrew S.¹²,Rondina Matthew T.¹³⁶⁸

Affiliation:

1. Molecular Medicine Program, University of Utah, Salt Lake City, UT;

2. Division of Pulmonary and Critical Care Medicine and

3. Division of General Internal Medicine, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT;

4. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Intermountain Medical Center, Murray, UT;

5. Rocky Mountain Center for Occupational and Environmental Health and

6. Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT;

7. George E. Wahlen Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT; and

8. Geriatric Research, Education, and Clinical Center, George E. Wahlen Salt Lake City Veterans Affairs Medical Center, Salt Lake City, UT

Abstract

Abstract In a Plenary Paper, Middleton and colleagues describe important transcriptional and translational changes in murine and human platelets during sepsis, elucidating the emerging role of platelets in the complications of systemic inflammatory illness.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/134/12/911/1223515/bloodbld2019000067.pdf

Reference44 articles.

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2. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference;Levy;Crit Care Med,2003

4. Thrombocytopenia in adult patients with sepsis: incidence, risk factors, and its association with clinical outcome;Venkata;J Intensive Care,2013

5. Platelet function in sepsis;Yaguchi;J Thromb Haemost,2004

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