RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis
Author:
Affiliation:
1. School of Medicine, University of Leeds, Leeds, United Kingdom; and
2. Faculty of Biology, Medicine and Health, University of Manchester, AV Hill Building, Manchester, United Kingdom
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/136/1/140/1747544/bloodbld2019004174.pdf
Reference25 articles.
1. Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels;Coste;Science,2010
2. Piezos thrive under pressure: mechanically activated ion channels in health and disease;Murthy;Nat Rev Mol Cell Biol,2017
3. Force Sensing by Piezo Channels in Cardiovascular Health and Disease;Beech;Arterioscler Thromb Vasc Biol,2019
4. Touch, Tension, and Transduction: The Function and Regulation of Piezo Ion Channels;Wu;Trends Biochem Sci,2017
5. Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis;Zarychanski;Blood,2012
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1. The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells;International Journal of Molecular Sciences;2024-01-24
2. A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation;Journal of General Physiology;2023-10-06
3. The cation‐leaky hereditary stomatocytosis syndromes: A tale of six proteins;British Journal of Haematology;2023-09-07
4. Small-molecule functional rescue of PIEZO1 channel variants associated with generalised lymphatic dysplasia;2023-08-04
5. PIEZO1 force sensing controls global lipid homeostasis;2023-07-25
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