Two to tango: engineered T cells against AML

Author:

Arber Caroline1ORCID

Affiliation:

1. Lausanne University Hospital

Publisher

American Society of Hematology

Reference10 articles.

1. A dual-receptor T-cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML;Dao;Blood,2024

2. T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant;Chapuis;Nat Med,2019

3. A high-avidity WT1-reactive T-cell receptor mediates recognition of peptide and processed antigen but not naturally occurring WT1-positive tumor cells;Jaigirdar;J Immunother,2016

4. Targeting an alternate Wilms' tumor antigen 1 peptide bypasses immunoproteasome dependency;Lahman;Sci Transl Med,2022

5. CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function;Ruggiero;Sci Transl Med,2022

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