Fattening up FLT3-ITD for the kill
Author:
Affiliation:
1. University of Alabama at Birmingham
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
https://ashpublications.org/blood/article-pdf/138/22/2158/1848152/bloodbld2021013182c.pdf
Reference9 articles.
1. Depalmitoylation rewires FLT3-ITD signaling and exacerbates leukemia progression;Lv;Blood.,2021
2. Targeting FLT3 mutations in AML: review of current knowledge and evidence;Daver;Leukemia.,2019
3. Gilteritinib: potent targeting of FLT3 mutations in AML;Levis;Blood Adv.,2020
4. Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes;Choudhary;Mol Cell.,2009
5. Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia;Reiter;Leukemia.,2018
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