Somatic <i>TP53</i> mutations are preleukemic events in acute lymphoblastic leukemia-Reference-Cited by-同舟云学术

Somatic TP53 mutations are preleukemic events in acute lymphoblastic leukemia

Published:2023-03-30 Issue:13 Volume:141 Page:1640-1644
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Chitadze Guranda¹²³^ORCID,Stengel Anna⁴,John-Klaua Cathrin¹,Bruckmüller Julien¹⁵^ORCID,Trautmann Heiko¹²,Kotrova Michaela¹²,Darzentas Franziska¹²,Kelm Miriam¹²,Pal Karol¹⁶^ORCID,Darzentas Nikos¹²,Bastian Lorenz¹²³,Kehden Britta¹²,Wessels Wiebke¹²,Ströh Aeint-Steffen¹²,Oberg Hans-Heinrich⁷,Altrock Philipp M.⁸,Baer Constance⁴,Meggendorfer Manja⁴,Gökbuget Nicola⁹,Baldus Claudia D.¹²³,Haferlach Claudia⁴,Brüggemann Monika¹²³^ORCID

Affiliation:

1. 1Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany

2. 2University Cancer Center Schleswig-Holstein, University Hospital Schleswig-Holstein, Kiel and Lübeck, Germany

3. 3Clinical Research Unit CATCH-ALL, Christian-Albrechts-University of Kiel, Kiel, Germany

4. 4Munich Leukemia Laboratory, Munich, Germany

5. 5Solana Research GmbH, Windeby, Germany

6. 6Central European Institute of Technology, Masaryk University, Brno, Czech Republic

7. 7Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany

8. 8Department of Evolutionary Theory, Max Planck Institute for Evolutionary Biology, Ploen, Germany

9. 9Department of Medicine II, Goethe University Hospital, Frankfurt, Germany

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

https://ashpublications.org/blood/article-pdf/141/13/1640/2040701/blood_bld-2022-017249-main.pdf

Reference16 articles.

1. The impact of TP53 mutations and TP53 deletions on survival varies between AML, ALL, MDS and CLL: an analysis of 3307 cases;Stengel;Leukemia,2017

2. Mutations of TP53 gene in adult acute lymphoblastic leukemia at diagnosis do not affect the achievement of hematologic response but correlate with early relapse and very poor survival;Salmoiraghi;Haematologica,2016

3. TP53 mutations are frequent in adult acute lymphoblastic leukemia cases negative for recurrent fusion genes and correlate with poor response to induction therapy;Chiaretti;Haematologica,2013

4. Acute lymphoblastic leukemia with low hypodiploid/near triploid karyotype is a specific clinical entity and exhibits a very high TP53 mutation frequency of 93%;Muhlbacher;Genes Chromosomes Cancer,2014

5. TP53 mutations in hypodiploid acute lymphoblastic leukemia;Comeaux;Cold Spring Harb Perspect Med,2017

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