Prognostic value and oncogenic landscape of TP53 alterations in adult and pediatric T-ALL

Author:

Simonin Mathieu123ORCID,Andrieu Guillaume P.12ORCID,Birsen Rudy45,Balsat Marie6,Hypolite Guillaume12,Courtois Lucien12,Graux Carlos7,Grardel Nathalie89ORCID,Cayuela Jean-Michel10,Huguet Françoise11ORCID,Chalandon Yves1213ORCID,Le Bris Yannick14ORCID,Macintyre Elizabeth13ORCID,Gandemer Virginie15ORCID,Petit Arnaud3ORCID,Rousselot Philippe1617ORCID,Baruchel André18,Bouscary Didier45,Hermine Olivier19,Boissel Nicolas20ORCID,Asnafi Vahid12

Affiliation:

1. 1Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Université de Paris Cité, Paris, France

2. 2Institut Necker-Enfants Malades, INSERM U1151, Paris, France

3. 3Department of Pediatric Hematology and Oncology, Assistance Publique-Hôpitaux de Paris, Armand Trousseau Hospital, Sorbonne Université, Paris, France

4. 4Department of Hematology, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Université de Paris Cité, Paris, France

5. 5Institut Cochin, INSERM U1016, Paris, France

6. 6Hospices Civils de Lyon, Service d'Hématologie Clinique, Centre Hospitalier Lyon-Sud, Pierre-Bénite, France

7. 7CHU UCLouvain Namur-Godinne, service d’Hématologie, Yvoir, Belgium

8. 8Laboratory of Hematology, CHRU Lille, Lille, France

9. 9INSERM U1172, Lille, France

10. 10Laboratory of Hematology and EA3518, Saint-Louis University Hospital, Université de Paris Cité, Paris, France

11. 11Department of Hematology, CHRU-Institut Universitaire de Cancer Toulouse-Oncopole, Toulouse, France

12. 12Division of Hematology, Department of Oncology, University Hospital of Geneva and Faculty of Medicine, University of Geneva, Geneva, Switzerland

13. 13Swiss Group for Clinical Cancer Research, Bern, Switzerland

14. 14Hematology Biology, Nantes University Hospital and Nantes-Angers Cancer and Immunology Research Center, Nantes, France

15. 15Department of Pediatric Hematology and Oncology, University Hospital of Rennes, Rennes, France

16. 16Department of Hematology, Centre Hospitalier de Versailles, Le Chesnay, France

17. 17Université Paris-Saclay, Communauté Paris-Saclay, France

18. 18Department of Pediatric Hematology and Immunology, Assistance Publique-Hôpitaux de Paris, Robert Debré Hospital, Université de Paris Cité, Paris, France

19. 19Department of Hematology, INSERM U1163, IMAGINE Institute, Paris University, Necker Hospital, Paris, France

20. 20Université Paris Cité, Institut de Recherche Saint-Louis, URP-3518, Publique-Hôpitaux de Paris, Saint-Louis University Hospital, Paris, France

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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