The lufaxin inhibitor caught in the act
Author:
Affiliation:
1. 1Aarhus University
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
https://ashpublications.org/blood/article-pdf/141/25/3017/2068642/blood_bld-2023-020507-c-main.pdf
Reference10 articles.
1. A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism;Andersen;Blood,2023
2. Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation;Ekdahl;Immunol Rev,2016
3. Structures of C3b in complex with factors B and D give insight into complement convertase formation;Forneris;Science,2010
4. Complement-coagulation connections;Conway;Blood Coagul Fibrinolysis,2018
5. Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo;Collin;Arterioscler Thromb Vasc Biol,2012
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