Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies-Reference-Cited by-同舟云学术

Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies

Published:2019-08-29 Issue:18 Volume:134 Page:1487-1497
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Lio Chan-Wang J.¹^ORCID,Yuita Hiroshi¹^ORCID,Rao Anjana¹²³⁴^ORCID

Affiliation:

1. Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA;

2. Department of Pharmacology and

3. Moores Cancer Center, University of California San Diego, La Jolla, CA; and

4. Sanford Consortium for Regenerative Medicine, San Diego, CA

Abstract

TET2 is frequently mutated in lymphoid and myeloid malignancy. Lio et al review the current understanding of the role of TET enzymes in lymphoid and myeloid malignancy, highlighting that loss of TET protein function can occur either by mutation or as a result of metabolic alteration.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/134/18/1487/1504078/bloodbld2019791475c.pdf

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