Proof of concept for a rapidly switchable universal CAR-T platform with UniCAR-T-CD123 in relapsed/refractory AML

Author:

Wermke Martin12,Kraus Sabrina3,Ehninger Armin4,Bargou Ralf C.5,Goebeler Maria-Elisabeth5,Middeke Jan Moritz12,Kreissig Carla6,von Bonin Malte12,Koedam Jan4,Pehl Michael4,Bornhäuser Martin12,Einsele Hermann3,Ehninger Gerhard4,Cartellieri Marc4ORCID

Affiliation:

1. Division of Hematology, Oncology and Stem Cell Transplantation, Medical Clinic I, Department of Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany;

2. National Center for Tumor Diseases, Dresden, Germany;

3. Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany;

4. GEMoaB GmbH, Dresden, Germany;

5. Comprehensive Cancer Center Mainfranken, Early Clinical Trials Unit, University Hospital Würzburg, Würzburg, Germany; and

6. Cellex Manufacturing Transports and Logistics GmbH, Cologne, Germany

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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