Combining pathological and cognitive tests scores: A novel data analytics process to improve dementia prediction models1

Author:

Alshehhi Talib,Ayesh Aladdin,Yang Yingjie,Chen Feng

Abstract

BACKGROUND: The term ‘dementia’ covers a range of progressive brain diseases from which many elderly people suffer. Traditional cognitive and pathological tests are currently used to detect dementia, however, applications using Artificial Intelligence (AI) methods have recently shown improved results from improved detection accuracy and efficiency. OBJECTIVE: This research paper investigates the efficacy of one type of data analytics called supervised learning to detect Alzheimer’s disease (AD) – a common dementia condition. METHODS: The aim is to evaluate cognitive tests and common biological markers (biomarkers) such as cerebrospinal fluid (CSF) to develop predictive classification systems for dementia detection. RESULTS: A data analytics process has been proposed, implemented, and tested against real data obtained from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) repository. CONCLUSION: The models showed good power in predicting AD levels, notably from specified cognitive tests’ scores and tauopathy related features.

Publisher

IOS Press

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