Höffding step and beyond: The impact of visual sensory impairment on cognitive performance in neuropsychological testing of survivors of acute methanol poisoning-Reference-Cited by-同舟云学术

Höffding step and beyond: The impact of visual sensory impairment on cognitive performance in neuropsychological testing of survivors of acute methanol poisoning

Published:2023-08-04 Issue:1 Volume:53 Page:51-60
ISSN:1053-8135
Container-title:NeuroRehabilitation
language:
Short-container-title:NRE

Author:

Bukacova Katerina¹,Mana Josef¹,Zakharov Sergey²,Diblík Pavel³,Pelclova Daniela²,Urban Pavel⁴,Klepiš Petr²,Klempíř Jiří¹,Libon David J.⁵,Růžička Evžen¹,Bezdicek Ondrej¹⁶^ORCID

Affiliation:

1. Centre of Clinical Neuroscience, Department of Neurology, First Faculty of Medicine, General University Hospital in Prague, Charles University, Prague, Czech Republic

2. Department of Occupational Medicine, First Faculty of Medicine, General University Hospital in Prague, Charles University, Prague, Czech Republic

3. Department of Ophthalmology, First Faculty of Medicine, General University Hospital in Prague, Charles University, Prague, Czech Republic

4. National Institute of Public Health, Prague, Czech Republic

5. Department of Geriatrics and Gerontology, Institute for Successful Aging, Department of Psychology, School of Osteopathic Medicine, Rowan University, Glassboro, NJ, USA

6. Department of Psychology, Faculty of Arts, Charles University, Prague, Czech Republic

Abstract

BACKGROUND: Sensory deficits can result in limitations regarding how well neuropsychological test findings can be interpreted. Only a few studies have investigated the influence of vision alteration on neuropsychological tests. In 2012 the Czech Republic experienced mass methanol poisoning. Methanol metabolites cause histotoxic hypoxia to the optic nerve. OBJECTIVE: In the current study, the effect of the toxic damage on the parts of the visual pathway on visual and non-visual neuropsychological measures was investigated using electrophysiological methods (visual evoked potential (VEP) and optical coherence tomography (OCT) with retinal nerve fibre layer (RNFL) thickness measurement. METHODS: 53 individuals who experienced methanol poisoning participated in this research (76% men; ages 24 to 74 years, mean = 43.8±14.6 years; education 11.9±1.4 years). Each participant underwent comprehensive neurological, ophthalmological, and neuropsychological examinations. RESULTS: The results of mixed-effect models revealed significant small to a medium association between the Stroop test weak interference and Grooved Pegboard with the left eye global, nasal and temporal RNFL thickness. Also, medium associations between the Finger Tapping test and the Stroop test weak interference and left eye temporal RNFL, right eye temporal RNFL, and the latency P1 of VEP in the left eye were significant. CONCLUSION: The results of this study found a small to medium association (r = .15– .33; p = .010– .046) between RNFL thickness and cognitive visual test performance. Careful interpretation is suggested regarding results obtained from visual tests of the executive or motor functioning with participants with RNFL decrease or other types of early visual processing damage.

Publisher

IOS Press

Subject

Neurology (clinical),Rehabilitation,Physical Therapy, Sports Therapy and Rehabilitation

Reference59 articles.

1. Alexander, D. M. , Trengove, C. , van Leeuwen, C. (2015) Donders is dead: Cortical traveling waves and the limits of mental chronometry in cognitive neuroscience. Cognitive Processing, 16(4), 365–375. https://doi.org/10.1007/s10339-015-0662-4

2. Arora, V. , Nijjar, I. B. S. , Multani, A. S. (2007) CASE REPORT MRI findings in methanol intoxication: A report of two cases. The British Journal of Radiology, 80, 243–246. https://doi.org/10.1259/bjr/40137535

3. Baltes, P. B. , Lindenberger, U. (1997) Emergence of a powerful connection between sensory and cognitive functions across the adult life span: A new window to the study of cognitive aging? Psychology and Aging, 12(1), 12–21. https://doi.org/10.1037/0882-7974.12.1.12

4. Bezdicek, O. , Lukavsky, J. , Stepankova, H. , Nikolai, T. , Axelrod, B. N. , Michalec, J. , Růžička, E. , Kopecek, M. (2015) The Stroop Test: Normative standards in older Czech adults and discriminative validity for mild cognitive impairment in Parkinsons disease. Journal of Clinical and Experimental Neuropsychology, 37(8), 794–807. https://doi.org/10.1080/13803395.2015.1057106 Prague.

5. Bezdicek, O. , Michalec, J. , Vaneckova, M. , Klempir, J. , Liskova, I. , Seidl, Z. , Janikova, B. , Miovsky, M. , Hubacek, J. , Diblik, P. , Kuthan, P. , Pilin, A. , Kurcova, I. , Fenclova, Z. , Petrik, V. , Navratil, T. , Pelclova, D. , Zakharov, S. , Ruzicka, E. (2017) Cognitive sequelae of methanol poisoning involve executive dysfunction and memory impairment in cross-sectional and long-term perspective. Alcohol, 59, 27–35. https://doi.org/10.1016/j.alcohol.2016.12.003