Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer’s Disease

Author:

Deters Kacie D.123,Risacher Shannon L.12,Kim Sungeun124,Nho Kwangsik12,West John D.1,Blennow Kaj5,Zetterberg Henrik56,Shaw Leslie M.7,Trojanowski John Q.7,Weiner Michael W.8,Saykin Andrew J.123,

Affiliation:

1. Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA

2. Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA

3. Program in Medical Neuroscience, Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA

4. Department of Electrical and Computer Engineering, State University of New York, Oswego, NY, USA

5. Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden

6. Department of Molecular Neuroscience, University College London Institute of Neurology, London, UK

7. Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA

8. Department of Radiology, Medicine, and Psychiatry, University of California San Francisco, San Francisco, CA, USA

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference18 articles.

1. Correlation of Alzheimer disease neuropathologic changes with cognitive status: A review of the literature;Nelson;J Neuropathol Exp Neurol,2012

2. Brier MR , Gordon B , Friedrichsen K , McCarthy J , Stern A , Christensen J , Owen C , Aldea P , Su Y , Hassenstab J , Cairns NJ , Holtzman DM , Fagan AM , Morris JC , Benzinger TL , Ances BM (2016) Tau and Abeta imaging, CSF measures, and cognition in Alzheimer’s disease. Sci Transl Med 8, 338ra366.

3. Prediction of conversion from mild cognitive impairment to Alzheimer’s disease dementia based upon biomarkers and neuropsychological test performance;Ewers;Neurobiol Aging,2012

4. CSF and blood biomarkers for the diagnosis of Alzheimer’s disease: A systematic review and meta-analysis;Olsson;Lancet Neurol,2016

5. Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: Results of a pilot study;Randall;Resuscitation,2013

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