Six Years Follow-Up of an 11-Year-Old Girl with Anti-HMGCR Myopathy-Reference-Cited by-同舟云学术

Six Years Follow-Up of an 11-Year-Old Girl with Anti-HMGCR Myopathy

Published:2024-07-02 Issue:4 Volume:11 Page:883-887
ISSN:2214-3599
Container-title:Journal of Neuromuscular Diseases
language:
Short-container-title:JND

Author:

Cavusoglu Dilek¹^ORCID,Talim Beril²^ORCID,Ekinci Gazanfer³^ORCID,Topaloglu Haluk⁴^ORCID

Affiliation:

1. Department of Pediatric Neurology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyon, Turkey

2. Department of Pediatrics, Pathology Unit, Hacettepe University, Ankara, Turkey

3. Department of Radiology, Yeditepe University School of Medicine, Istanbul, Turkey

4. Department of Pediatrics, Yeditepe University, Istanbul, Turkey

Abstract

Anti-HMGCR myopathy is decribed as an immune-mediated necrotizing myopathy which is characterised by subacute, progressive proximal muscle weakness and elevated creatine kinase (CK) level. In pediatric population, anti-HMGCR myopathy has been reported solely as small case reports, albeit rare. Although treatment consensus has not yet been established, proper treatment with several immunomodulators to include IVIg can show remarkable improvement. We report an 11-year-old-girl diagnosed with anti-HMGCR myopathy with 6 years of follow-up.

Publisher

IOS Press

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