Two-Year Longitudinal Monitoring of Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer’s Disease Using Topographical Biomarkers Derived from Functional Magnetic Resonance Imaging and Electroencephalographic Activity

Author:

Jovicich Jorge1,Babiloni Claudio23,Ferrari Clarissa4,Marizzoni Moira5,Moretti Davide V.6,Del Percio Claudio7,Lizio Roberta2,Lopez Susanna2,Galluzzi Samantha5,Albani Diego8,Cavaliere Libera5,Minati Ludovico1,Didic Mira910,Fiedler Ute11,Forloni Gianluigi8,Hensch Tilman12,Molinuevo José Luis13,Bartrés Faz David1415,Nobili Flavio1617,Orlandi Daniele5,Parnetti Lucilla18,Farotti Lucia18,Costa Cinzia18,Payoux Pierre19,Rossini Paolo Maria20,Marra Camillo20,Schönknecht Peter12,Soricelli Andrea7,Noce Giuseppe7,Salvatore Marco7,Tsolaki Magda21,Visser Pieter Jelle22,Richardson Jill C.23,Wiltfang Jens111124,Bordet Régis25,Blin Olivier26,Frisoniand Giovanni B.527,

Affiliation:

1. Center for Mind/Brain Sciences, University of Trento, Italy

2. Department of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, Rome, Italy

3. Department of Neuroscience, IRCCS-Hospital San Raffaele Pisana of Rome and Cassino, Rome and Cassino, Italy

4. Unit of Statistics, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy

5. Lab Alzheimer’s Neuroimaging & Epidemiology, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy

6. Alzheimer’s Epidemiology and Rehabilitation in Alzheimer’s disease Operative Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy

7. IRCCS SDN, Napoli, Italy

8. Department of Neuroscience, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy

9. Aix-Marseille Université, INSERM, INS UMR_S 1106, Marseille, France; Service de Neurologie et Neuropsychologie, APHM Hôpital Timone Adultes, Marseille, France

10. APHM, Timone, Service de Neurologie et Neuropsychologie, APHM Hôpital Timone Adultes, Marseille, France

11. Department of Psychiatry and Psychotherapy, LVR-Hospital Essen, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany

12. Department of Psychiatry and Psychotherapy, University of Leipzig, Leipzig, Germany

13. Alzheimer’s disease and other cognitive disorders unit, Neurology Service, ICN Hospital Clinic i Universitari and Pasqual Maragall Foundation Barcelona, Spain

14. Department of Medicine, Medical Psychology Unit, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain

15. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

16. Department of Neuroscience (DINOGMI), Neurology Clinic, University of Genoa, Italy

17. U.O. Clinica Neurologica, IRCCS Ospedale Policlinico San Martino, Genova, Italy

18. Clinica Neurologica, Università di Perugia, Ospedale Santa Maria della Misericordia, Perugia, Italy

19. ToNIC, Toulouse NeuroImaging Center, Université de Toulouse, Inserm, UPS, France

20. Department of Gerontology, Neurosciences & Orthopedics, Catholic University, Policlinic A. Gemelli Foundation-IRCCS, Rome, Italy

21. 1st University Department of Neurology, AHEPA Hospital, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Makedonia, Greece

22. Department of Neurology, Alzheimer Centre, VU Medical Centre, Amsterdam, The Netherlands

23. Neurosciences Therapeutic Area, GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, UK

24. Department of Psychiatry and Psychotherapy, University Medical Center (UMG), Georg-August-University, Goettingen, Germany

25. University of Lille, Inserm, CHU Lille, U1171 - Degenerative and vascular cognitive disorders, Lille, France

26. Aix Marseille University, UMR-CNRS 7289, Service de Pharmacologie Clinique, AP-HM, Marseille, France

27. Memory Clinic and LANVIE - Laboratory of Neuroimaging of Aging, University Hospitals and University of Geneva, Geneva, Switzerland

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

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