Transcriptional Assessment of Striatal mRNAs as Valid Biomarkers of Disease Progression in Three Mouse Models of Huntington’s Disease
Author:
Affiliation:
1. PsychoGenics Inc., Paramus, NJ, USA
2. Department of Psychiatry and Behavioral Sciences, Division of Neurobiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
3. CHDI Management/CHDI Foundation, Inc, Princeton, NJ, USA
Publisher
IOS Press
Subject
Cellular and Molecular Neuroscience,Neurology (clinical)
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3. Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain;Luthi-Carter;Hum Mol Genet,2002
4. Polyglutamine pathogenesis: Emergence of unifying mechanisms for Huntington’s disease and related disorders;Ross;Neuron,2002
5. Transcriptional signatures in Huntington’s disease;Cha;Prog Neurobiol,2007
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1. Neuronal and astrocytic contributions to Huntington’s disease dissected with zinc finger protein transcriptional repressors;Cell Reports;2023-01
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