Application of artificial intelligence for the classification of the clinical outcome and therapy in patients with viral infections: The case of COVID-19

Author:

Badnjević Almir1,Pokvić Lejla Gurbeta2,Smajlhodžić-Deljo Merima2,Spahić Lemana2,Bego Tamer1,Meseldžić Neven1,Prnjavorac Lejla3,Prnjavorac Besim2,Bedak Omer3

Affiliation:

1. Department of Pharmaceutical Biochemistry and Laboratory Diagnostics, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

2. Verlab Research Institute for Biomedical Engineering, Medical Devices and Artificial Intelligence, Sarajevo, Bosnia and Herzegovina

3. General Hospital Tešanj, Tešanj, Bosnia and Herzegovina

Abstract

BACKGROUND: With the end of the coronavirus disease 2019 (COVID-19) pandemic, it becomes intriguing to observe the impact of innovative digital technologies on the diagnosis and management of diseases, in order to improve clinical outcomes for patients. OBJECTIVE: The research aims to enhance diagnostics, prediction, and personalized treatment for patients across three classes of clinical severity (mild, moderate, and severe). What sets this study apart is its innovative approach, wherein classification extends beyond mere disease presence, encompassing the classification of disease severity. This novel perspective lays the foundation for a crucial decision support system during patient triage. METHODS: An artificial neural network, as a deep learning technique, enabled the development of a complex model based on the analysis of data collected during the process of diagnosing and treating 1000 patients at the Tešanj General Hospital, Bosnia and Herzegovina. RESULTS: The final model achieved a classification accuracy of 82.4% on the validation data set, which testifies to the successful application of the artificial neural network in the classification of clinical outcomes and therapy in patients infected with viral infections. CONCLUSION: The results obtained show that expert systems are valuable tools for decision support in healthcare in communities with limited resources and increased demands. The research has the potential to improve patient care for future epidemics and pandemics.

Publisher

IOS Press

Subject

Health Informatics,Biomedical Engineering,Information Systems,Biomaterials,Bioengineering,Biophysics

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