Early Neurodegeneration in R6/2 Mice Carrying the Huntington’s Disease Mutation with a Super-Expanded CAG Repeat, Despite Normal Lifespan
Author:
Affiliation:
1. Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
Publisher
IOS Press
Subject
Cellular and Molecular Neuroscience,Clinical Neurology
Reference85 articles.
1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes;Huntington’s Disease Collaborative Research Group;Cell,1993
2. Huntington’s disease: A clinical review;Roos;Orphanet J Rare Dis,2010
3. Bates G , Tabrizi S , Jones L . Huntington’s disease, 4th ed. Oxford: Oxford University Press; 2014.
4. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain;DiFiglia;Science,1997
5. Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease;Sapp;J Neuropathol Exp Neurol,1999
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1. The length of uninterrupted CAG repeats in stem regions of repeat disease associated hairpins determines the amount of short CAG oligonucleotides that are toxic to cells through RNA interference;Cell Death & Disease;2022-12-30
2. Approaches to Sequence the HTT CAG Repeat Expansion and Quantify Repeat Length Variation;Journal of Huntington's Disease;2021-02-09
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