Geroscience and the Fight Against Alzheimer’s Disease: Between Myth and Reality

Author:

Boccardi Virginia1ORCID,Ruggiero Carmelinda1,Cecchetti Roberta1,Mecocci Patrizia12

Affiliation:

1. Department of Medicine and Surgery, Division of Gerontology and Geriatrics, University of Perugia, Perugia, Italy

2. Department of Neurobiology, Division of Clinical Geriatrics, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden

Abstract

 Aging is associated with a gradual decline in cellular stability, leading to a decrease in overall health. In the brain, this process is closely linked with an increased risk of neurodegenerative diseases, including Alzheimer’s disease. Understanding the mechanisms of brain aging is crucial for developing strategies aimed at enhancing both lifespan and health span. Recent advancements in geroscience, the study of the relationship between aging and age-related diseases, have begun to redefine our understanding of Alzheimer’s disease, guiding the development of preventive medical strategies that target the aging process itself rather than merely addressing the symptomatic manifestations of the disease.

Publisher

IOS Press

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