Safety, Tolerability, and Pharmacokinetics of Crenezumab in Patients with Mild-to-Moderate Alzheimer’s Disease Treated with Escalating Doses for up to 133 Weeks
Author:
Affiliation:
1. Genentech, Inc., South San Francisco, CA, USA
2. Columbia University Irving Medical Center, New York, NY, USA
3. F. Hoffmann-La Roche Ltd, Basel, Switzerland
4. F. Hoffmann-La Roche Ltd, Welwyn Garden City, UK
Publisher
IOS Press
Subject
Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience
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4. Quantitative analysis of senile plaques in Alzheimer’s disease: Observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome);Hyman;Proc Natl Acad Sci U S A,1995
5. Impaired spine stability underlies plaque-related spine loss in an Alzheimer’s disease mouse model;Spires-Jones;Am J Pathol,2007
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