MicroRNA-539 inhibits the progression of Wilms’ Tumor through downregulation of JAG1 and Notch1/3

Author:

Su Hailong11,Wang Xuebo21,Song Jingjing3,Wang Yongjiao4,Zhao Yingchun5,Meng Juan6

Affiliation:

1. Department of Pediatric Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China

2. Department of Clinical Laboratory, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China

3. Department of Clinical Laboratory, People’s Hospital of Rizhao, Rizhao, Shandong, China

4. Department of Internal Medicine, Community Health Service Center, Zao Yuan Street Office of Zhangqiu District, Jinan, Shandong, China

5. Department of Pediatrics, The People’s Hospital of Zhangqiu Area, Jinan, Shandong, China

6. Department of Blood Transfusion, Yankuang New Journey General Hospital, Zoucheng, Shandong, China

Publisher

IOS Press

Subject

Cancer Research,Genetics,Oncology,General Medicine

Reference33 articles.

1. Up-regulation of miR-190b promoted growth, invasion, migration and inhibited apoptosis of Wilms’ tumor cells by repressing the PTEN expression;An;European Review for Medical and Pharmacological Sciences,2018

2. The role of Notch signaling in kidney development and disease;Barak;Advances in Experimental Medicine and Biology,2012

3. Abdominal masses in children: Neuroblastoma, Wilms tumor, and other considerations;Brodeur;Pediatrics in Review,1991

4. miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT;Chen;Experimental Cell Research,2017

5. The putative tumor suppressor miR-524-5p directly targets Jagged-1 and Hes-1 in glioma;Chen;Carcinogenesis,2012

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